Name | triethyl 3-methyl-4-phosphono-2-buten-oate (cis+trans) |
Synonyms | TRIETHYL 4-PHOSPHONOSENECIOATE TRIETHYL-3-METHYLPHOSPHONOCROTONATE TRIETHYL 3-METHYL-4-PHOSPHONOCROTONATE TRIETHYL 3-METHYL-4-PHOSPHONO-2-BUTENOATE triethyl 3-methyl-4-phosphono-2-buten-oate (cis+trans) DIETHYL(3-ETHOXYCARBONYL-2-METHYL-PROP-2-ENYL)PHOSPHONATE triethyl 3-methyl-4-phosphono-2-butenoate, mixture of cis and trans |
CAS | 41891-54-7 |
EINECS | 202-620-9 |
InChI | InChI=1/C11H21O5P/c1-5-14-11(12)8-10(4)9-17(13,15-6-2)16-7-3/h8H,5-7,9H2,1-4H3/b10-8+ |
InChIKey | OQKGPUSERILONW-CSKARUKUSA-N |
Molecular Formula | C11H21O5P |
Molar Mass | 264.26 |
Density | 1.089g/mLat 25°C(lit.) |
Boling Point | 284-287°C(lit.) |
Flash Point | >230°F |
Solubility | Chloroform, Ethyl Acetate |
Vapor Presure | 6.2E-05mmHg at 25°C |
Appearance | Oil |
Color | Clear Colourless to Pale Yellow |
BRN | 2417880 |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.46 |
Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29319090 |
Uses | Triethyl 3-methyl-4-phosphonobutenoic acid is used to synthesize effective insect growth regulators. It is also used to synthesize retinoic acid. |
Application | 3-methyl-4-phosphonobutenoic acid triethyl ester is a phosphonobutenoic acid derivative, due to its high functionality, Used in the synthesis of various compounds. Triethyl 3-methyl-4-phosphonobutenoic acid can be used to prepare (2E,4E,6E,8E)-3, 7-dimethyl-9-(2,6, 6-trimethyl-1-cyclohexene-1-yl) non-2, 4,6, 8-tetraenoic acid (generic name: retinoic acid). |
preparation | 440g triethyl phosphite was added to a 3000mL four-mouth flask with thermometer and cooling tube, and heated to an internal temperature of 110 ℃ using an oil bath . In 100 minutes, 1500g(GC pure degree 90%) of ethyl 4-bromo-3-methylbutenoate/monochlorobenzene solution was added dropwise. After dropping, the solution of 3-methyl-4-phosphonobutenoic acid triethyl ester/mono-chlorobenzene solution was obtained by reacting at an internal temperature of 110~120 ℃ for 3 hours at GC purity 81% 1700g. |